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Samuel and Lourdes are a humble marriage that go out of their way taking care of the land and their Lord properties. The owner of the house is Víctor, an ancient vampire that only feeds himself with the blood of bad people. Generation over generation, Samuel's family has been in charge of the duty of protecting their Lord but now, Samuel and Lourdes have two problems: they can not have a baby and a mysterious vampire relative arrives to the place turning everything upside down.

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In a near futures a young woman, Anna, suffers a progressive addiction to a drug which begins to have bizarre side-effects, threatening to ruin the already tenuous relationship she has with her mother. With communication almost non-existent, her mother decides to take an extraordinary step to restore Anna's innocence.

Flor thinks she's in vacation with her father, when in reality Pedro is kidnapping her due to the fear of not seeing her again. When Flor discovers the truth, she escapes. Érica, her mother, looks for her desperately.

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70-year-old Malena gets a second chance at life when she magically turns into her 22-year-old self. Now, posing as "Maria" to hide her true identity, she becomes the lead singer of her grandson's band and tries to recover her dream of singing, which she had to give up at some point.

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